Fig. 5: Ldb1 displays anti-tumor efficacy in a mouse leukemia model.
From: LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1
A Schematic diagram of experimental design. B Representative bioluminescent images of mice treated with Ldb1 knockdown P388D1.ffluc cells or sh-NC-P388D1.ffluc cells. C Comparison of the maximum standard Avg radiance uptake value. D Female sh-Ldb1-treated mice had significantly prolonged survival compared with the controls. E Different sizes and weights of liver and spleen, from sh-NC or sh-Ldb1 mices. Biological image of Avg radiance uptake by liver and spleen tissue from BALB/c mice. F Representative images of HE staining and IHC staining of BALB/c mice livers.
