Fig. 1: Expression of Plk1 in patients and mice with kidney fibrosis. | Cell Death & Disease

Fig. 1: Expression of Plk1 in patients and mice with kidney fibrosis.

From: Plk1 promotes renal tubulointerstitial fibrosis by targeting autophagy/lysosome axis

Fig. 1

A Representative image of immunohistochemistry staining of Plk1 in kidneys of control and CKD patients. scale bar = 50 µm. n = 7–15. B Representative image of immunostaining of Plk1 in kidneys of sham and UUO mice. scale bar = 50 µm. n = 6. C Representative image of double immunofluorescent staining of Plk1/FSP1 (left) or Plk1/LTL (right) in control and CKD patient kidneys. D Representative image of double immunofluorescent staining of Plk1/FSP1 (left) or Plk1/LTL (right) in sham and UUO mice kidneys. scale bar = 50 µm. E, F Western blot and qRT-PCR analysis of Plk1 in sham and UUO mice. n = 7. *P < 0.05, **P < 0.01, ***P < 0.001.

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