Fig. 5: Receiving skin graft from WT mice evokes response to imiquimod stimulation in Gsdmd−/− mice.
From: Gasdermin D-mediated keratinocyte pyroptosis as a key step in psoriasis pathogenesis
A Flowchart of the skin transplant experiment. B The skin appearances were shown (n = 3). C The schematic diagram of obtained skin samples for H&E staining and immunohistochemistry study was indicated. D Histological features of different groups were shown (n = 3). E The epidermal thickness was measured by Image J software (for each group, n = 3). F The levels of loricrin and K5 were shown by immunohistochemistry study (n = 3). Scale bar is 2.5 mm in overview images (D and F). Scale bar is 100 μm (D) or 250 μm (F) in zoom images. *p < 0.05, **p < 0.01, ***p < 0.001.
