Fig. 6: A schematic diagram of this study indicated that Dlk2-Syap1-Akt axis in osteoclastogenesis.
From: Dlk2 interacts with Syap1 to activate Akt signaling pathway during osteoclast formation
Dlk2 deletion in osteoclasts suppressed osteoclastogenesis mainly by inhibiting Syap1 downstream cascades including the AktSer473, ERK1/2 and p38 phosphorylation.
