Fig. 6: SIRT4 regulated ferroptosis in vivo and in vitro.
From: Sirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosis
A–B Representative IHC staining of 4-HNE in the pancreas of mice. Scale bar = 100 µm. C–D Western blot of different types of ferroptosis-related proteins (ACSL4, GPX4, SLC7A11) in pancreas of mice. E–F The protein expression level of ferroptosis-related proteins (ACSL4, GPX4, SLC7A11) in AR42J cells. A–F used GAPDH as the reference protein. *P < 0.05, **P < 0.01, ***P < 0.001, ns. not significant. n = 6 per group.
