Fig. 3: SFN mitigates TNF-a and IL-22-induced activation of inflammatory pathways and proliferation in HaCaT cells. | Cell Death & Disease

Fig. 3: SFN mitigates TNF-a and IL-22-induced activation of inflammatory pathways and proliferation in HaCaT cells.

From: Sulforaphane alleviates psoriasis by enhancing antioxidant defense through KEAP1-NRF2 Pathway activation and attenuating inflammatory signaling

Fig. 3

a The expression of p-STAT3, STAT3, K16, and K17 in response to SFN and IL-22 (25 ng/ml) treatment was determined by western blotting. b The relative expression levels were analyzed by normalization to GAPDH. c Western blot analysis of the protein expression of p-IκBα, IκBα, IL-1β, K16 and K17. d The relative protein levels were assessed by ImageJ software. Statistical significance was determined by one-way ANOVA analysis. *p < 0.05, **p < 0.01 and ***p < 0.001.

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