Fig. 3: S100A16 modulates the expression of HIF-1α and HRD1 in NRK-52E cells.
From: HIF-1α participates in the regulation of S100A16-HRD1-GSK3β/CK1α pathway in renal hypoxia injury
A Western blots of HIF-1α, HRD1, GSK-3β, β-catenin, and S100A16 in normal or H/R conditions using S100A16−/− cells. B Quantitation of western blot data for HIF-1α, HRD1, GSK-3β, and β-catenin in A. **P < 0.01, *P < 0.05. C The transcriptional expressions of Hif-1α and Syvn1 were tested by real-time PCR in normal or H/R conditions using the S100A16−/− cell line. **P < 0.01, *P < 0.05. D Western blots of HIF-1α, HRD1, GSK-3β, β-catenin, and S100A16 in NRK-52E cells overexpressed with S100A16. E Quantitation of the expression of HIF-1α, HRD1, GSK-3β, and β-catenin in D. **P < 0.01; *P < 0.05. F The transcriptional expressions of Hif-1α and Syvn1 were tested by real-time PCR in S100A16 overexpressing NRK-52E cells. **P < 0.01; *P < 0.05.
