Table 1 Clinicopathological correlation of FASN expression in Human liver cancer.

From: Deficiency of SIAH1 promotes the formation of filopodia by increasing the accumulation of FASN in liver cancer

Clinicopathological features

 

FASN

low

FASN high

P value

Gender

Male

28

24

>0.9999

 

Female

10

8

 

Tumor size, cm

<5

22

10

0.0321*

 

≥5

16

22

 

Number of tumor nodules

1

30

23

0.5804

 

≥2

8

9

 

Venous invasion

Present

13

21

0.0158*

 

Absent

25

11

 

Tumor microsatellite formation

Present

17

18

0.472

 

Absent

21

14

 

Direct liver invasion

Present

15

22

0.0145*

 

Absent

23

10

 

Tumor encapsulation

Present

20

14

0.4823

 

Absent

18

18

 

Cellular differentiation

according to Edmondson’s grading

Grades l

16

13

0.9388

 

Grades Il–IV

23

18

 

Background liver diseases

Normal and chronic hepatitis

17

12

0.7134

 

Cirrhosis

13

14

 
 

Steatohepatitis

8

6

 

T stage

T1

11

7

0.5

 

T2-4

27

25

 

N stage

N0

37

31

＞0.999

 

N1

1

1

 

M stage

M0

38

32

＞0.999

 

M1

0

0

 

MVI

M0

23

19

＞0.999

 

M1,M2

15

13

 
  1. *P <0.05. FASN high or low were grouped mainly according to the median protein level.
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