Fig. 5: LINC01637 promotes the progression of UM in vivo and in vitro. | Cell Death & Disease

Fig. 5: LINC01637 promotes the progression of UM in vivo and in vitro.

From: STAT6/LINC01637 axis regulates tumor growth via autophagy and pharmacological targeting STAT6 as a novel strategy for uveal melanoma

Fig. 5

A, C The level of LINC01637 mRNA in UM cells with reduced expression of LINC01637; (B, D) Analysis of the proliferation of UM cells with LINC01637 knockdown by CCK8 assay; (E, G) The level of LINC01637 mRNA in UM cells that have an increased amount of LINC01637; (F, H) Analysis of the proliferation of UM cells overexpressing LINC01637 by CCK8 assay; (I, J) Examination of the migration and invasion of UM cells under LINC01637 knockdown; (K, L) Examination of the migration and invasion of UM cells overexpressing LINC01637; (M) The volume of tumors formed in the LV-NC group and LV-LINC01637 group; (N) The weight of tumors formed in the LV-NC group and LV-LINC01637 group; (O) Photographic images of tumors from the LV-NC group and LV-LINC01637 group; (Scale bar: 100 µm; Data were presented as the mean ± SD; n = 3–6; *p < 0.05, **p < 0.01, ***p < 0.001).

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