Fig. 2: FASN promotes cancer progression through autophagy enhancement. | Cell Death & Disease

Fig. 2: FASN promotes cancer progression through autophagy enhancement.

From: VCP enhances autophagy-related osteosarcoma progression by recruiting USP2 to inhibit ubiquitination and degradation of FASN

Fig. 2

A–C Representative images (left) and the quantification (right) of Edu, colony formation and flow cytometry assay showing the growth and apoptotic rate of 143B and U2OS cells stably transfected with Ci-ATG5 or Ca-FASN or co-transfected with Ci-ATG5. D Immunofluorescence assay for the detection of the fluorescence intensity of cell proliferation protein (PCNA) and cellular anti-apoptotic protein (Bcl-xl) in 143B and U2OS cells stably transfected with Ci-ATG5 or Ca-FASN or co-transfected with Ci-ATG5. Scale bar: 50 µm *P < 0.05.

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