Fig. 2: ME2 methylation promotes proliferation and invasive metastasis of HCC cells. | Cell Death & Disease

Fig. 2: ME2 methylation promotes proliferation and invasive metastasis of HCC cells.

From: PRMT1-mediated methylation of ME2 promotes hepatocellular carcinoma growth by inhibiting ubiquitination

Fig. 2

A Plate cloning assay to analyze the colony forming ability of ME2-WT and ME2-MUT(R67K) on HCC cells. B CCK-8 assay to analyze the effects of ME2-WT and ME2-MUT(R67K) on HCC cell activity. C Cell suspension culture to analyze the effect of ME2-WT and ME2-MUT(R67K) on the stemness of HCC cells. D Transwell migration and invasion assay to analyze the effect of ME2-WT and ME2-MUT(R67K) on the invasive transfer ability of HCC cells. E Cell scratch assay to analyze the effect of ME2-WT and ME2-MUT(R67K) on the migration ability of HCC cells. **P < 0.01; ***P < 0.001.

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