Fig. 6: The CB1 cannabinoid receptor agonist ACEA reduced the expression of mitochondrial fission-associated proteins in rats after ischemic brain injury. | Cell Death Discovery

Fig. 6: The CB1 cannabinoid receptor agonist ACEA reduced the expression of mitochondrial fission-associated proteins in rats after ischemic brain injury.

From: Cannabinoid CB1 receptor agonist ACEA alleviates brain ischemia/reperfusion injury via CB1–Drp1 pathway

Fig. 6

A The CB1 antagonist AM251 reversed the ACEA-induced upregulation of mitochondrial CB1 expression. B Western blot results of Drp1, Fis1 and Mff expression in rats. C AM251 reversed the ACEA-induced inhibition of Drp1 expression in rats after brain ischemia. D AM251 reversed the ACEA-induced inhibition of Fis1 expression. E AM251 reversed the ACEA-induced inhibition of Mff expression. *p < 0.05; NS no significance.

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