Fig. 3: LYPLAL1-AS1 is positively correlated with adipogenic markers in human adipose tissues and promotes de novo adipogenesis in vivo. | Cell Death Discovery

Fig. 3: LYPLAL1-AS1 is positively correlated with adipogenic markers in human adipose tissues and promotes de novo adipogenesis in vivo.

From: Long noncoding RNA LYPLAL1-AS1 regulates adipogenic differentiation of human mesenchymal stem cells by targeting desmoplakin and inhibiting the Wnt/β-catenin pathway

Fig. 3

a qRT-PCR analysis of adipogenic markers (PPARγ, AP2, and CEBPα) and the correlation analysis for each marker pair among 28 clinical adipose tissue samples. The internal control was GAPDH. b qRT-PCR analysis of LYPLAL1-AS1 and adipogenic markers (PPARγ, AP2, and CEBPα) among 28 clinical adipose tissue samples. c, d Representative H&E staining images for de novo adipogenesis in NOD/SCID nude mice injected with the indicated hAMSCs (c) and quantification of the number of adipocytes 8 weeks after injection (d). The quantitative data were normalized to GAPDH, n = 3; data are shown as the mean ± SD, n = 28; **P < 0.01; scale bars: 200 µm.

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