Fig. 2: Gas6, Gas6/alb, and sAxl/alb in liver fibrosis. | Cell Death Discovery

Fig. 2: Gas6, Gas6/alb, and sAxl/alb in liver fibrosis.

From: Gas6 in chronic liver disease—a novel blood-based biomarker for liver fibrosis

Fig. 2

A Analysis of Gas6 and Gas6/alb serum levels in patients without fibrosis (F0, n = 68), with mild fibrosis (F1, n = 82), moderate fibrosis (F2, n = 65), advanced fibrosis (F3, n = 31) and cirrhosis (F4, n = 61) as assessed by liver biopsy. B–D Comparison of the diagnostic accuracy shown as area under the curve (AUC) of sAxl/alb and Gas6/alb and FIB-4 for B significant fibrosis (≥ F2) and C advanced fibrosis (≥ F3) as well as (D) liver cirrhosis (F4) according to fibrosis grading based on liver histology. Outliers are marked. F, fibrosis grade. Statistical significant differences are expressed as asterisks: ***P < 0.001.

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