Fig. 1: Effect of Prx II on psoriasis in mice. | Cell Death Discovery

Fig. 1: Effect of Prx II on psoriasis in mice.

From: Depletion of peroxiredoxin II promotes keratinocyte apoptosis and alleviates psoriatic skin lesions via the PI3K/AKT/GSK3β signaling axis

Fig. 1

A Damage to skin on the back of mice post IMQ treatment in Prx II+/+ mice and Prx II−/− mice (n = 6 in each group). B Histological changes in mouse skin as seen by H&E staining. C Skin thickness is reduced in Prx II−/− mice compared to Prx II+/+ mice. The data are represented by the mean ± SD (n = 6). D Histological evaluation reveals the presence of microabscesses. E, F Levels of serum L-17 and IL-22 as measured by enzyme-linked immunosorbent assay (ELISA). The data are represented by the mean ± SEM of three separate samples. (**p < 0.01).

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