Fig. 1: TIALD expression is down-regulated and associated with prognosis in HCC. | Cell Death Discovery

Fig. 1: TIALD expression is down-regulated and associated with prognosis in HCC.

From: LncRNA TIALD contributes to hepatocellular carcinoma metastasis via inducing AURKA lysosomal degradation

Fig. 1

A Heat-map of the 21 differentially expressed lncRNAs in 8 paired HCC tumor and adjacent para-tumor tissues. B Relative expression level of TIALD in adjacent para-tumor tissues (n = 50) and tumor tissues (n = 371) from TCGA cohort. C RT-qPCR validation of TIALD expression in another cohort of 110 HCC patients with paired tumor and para-tumor tissues. 18 S rRNA was used as internal control. Student’s t-test was used to compare the difference between para-tumor and tumor tissues. D Relative expression of TIALD in HCC patient with or without vascular invasion. E Differential expression levels of TIALD in HCC patient with low differentiation and high differentiation. F Relative expression of TIALD in HCC patient with recurrence or not. G, H Kaplan–Meier analysis revealed that low expression of TIALD significantly associated with shorter Overall survival (G) and Recurrence free survival (H).

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