Fig. 5: NTRK1 knockdown suppressed mitophagy in mouse neurons. | Cell Death Discovery

Fig. 5: NTRK1 knockdown suppressed mitophagy in mouse neurons.

From: NTRK1 knockdown induces mouse cognitive impairment and hippocampal neuronal damage through mitophagy suppression via inactivating the AMPK/ULK1/FUNDC1 pathway

Fig. 5

A, B Mitochondria were extracted from mouse neurons. WB was performed, and it was revealed that NTRK1 knockdown suppressed mitophagy in mouse neurons. n = 3. C, D The results of TOMM20/LC3-II fluorescence staining indicated that silencing NTRK1 reduced the expression of Parkin1 in the mitochondria of mouse neurons. n = 3. **P < 0.01.

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