Fig. 1: Schematic illustration of MPI/FLI/CT imaging of infiltrating neutrophils to identify AAA.

Targeted nanoprobes PEG–Fe3O4–Ly6G–Cy7 (Ly6G NPs) were synthesized by coupling Ly6G antibody with Fe3O4@PEG–COOH and Cy7–NHS. Ly6G NPs were injected into AAA mice via the tail vein and specifically bound to neutrophils infiltrated in diseased vessels. AAA was functionally imaged in vivo by MPI/FLI/CT imaging. Created with BioRender.com.