Fig. 5: MPI/FLI/CT imaging of AAA lesions in mice by intravenous injection of Ly6G NPs. | Cell Death Discovery

Fig. 5: MPI/FLI/CT imaging of AAA lesions in mice by intravenous injection of Ly6G NPs.

From: Highly sensitive magnetic particle imaging of abdominal aortic aneurysm NETosis with anti-Ly6G iron oxide nanoparticles

Fig. 5

A MPI in vivo imaging of normal mice and AAA was performed 24 h after injection of Ly6G NPs (n = 3). B Mice were necropsied, and the aorta was isolated intact for ex vivo MPI scanning imaging (n = 3). C FLI in vivo imaging was performed on normal mice and AAA 24 h after injection of Ly6G NPs (n = 3). D Mice were necropsied, and aortas were isolated intact for ex vivo FLI scanning imaging (n = 3). E The fused images of MPI 3D data with CT data of AAA mice. F Tissue sections of abdominal aorta from normal and AAA mice were stained with H&E, EVG, and Prussian blue, respectively. G AAA mice injected with Ly6G NPs 24 h after the injection were put to death, and the diseased vessels were hyalinized and labeled by IF, and then 3D tissue imaging was acquired by light-sheet microscopy.

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