Fig. 9: Enhanced expression of PLCB4 by formation of AR-BRD4 transcriptional regulatory complex. | Cell Death Discovery

Fig. 9: Enhanced expression of PLCB4 by formation of AR-BRD4 transcriptional regulatory complex.

From: Androgen-induced AR-BRD4 transcriptional regulatory complex promotes malignant proliferation of osteosarcoma cells

Fig. 9

A The impact of individual and combined inhibition of AR and BRD4 on PLCB4 mRNA and protein expression levels was assessed using RT-qPCR (B) and western blot analysis (C). D mIF analysis was performed to evaluate the expression levels of PLCB4 in each groups. Statistical significance was determined using Dunnett’s test for one-way ANOVA. *P < 0.05; **P < 0.01; ***P < 0.005.

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