Fig. 2: Aberrant transcriptome in Srsf3 mutant oocytes. | Cell Discovery

Fig. 2: Aberrant transcriptome in Srsf3 mutant oocytes.

From: SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements

Fig. 2

a A heatmap shows the Spearman correlation of gene expression between control and mutant oocytes in our single cell RNA-Seq data and oocytes and early mouse preimplantation embryos in previously published single cell RNA-seq data29. b PCA plot using the 5000 genes with the highest variance across all samples, axes are labeled to include the percentage of variance explained. c A heatmap showing the transcript level of key genes that promote or inhibit meiosis in control and mutant oocytes. The color indicates the expression level

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