Fig. 2: Inhibitor binding analysis.
From: Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter
a JX-078 binding mode in LAT1. b The hydrophobic interactions around the tail of JX-078. c LAT1 has a broad extracellular vestibule above JX-078. d Comparison of the binding mode of the three inhibitors. JX-075, JX-078, and JX-119 are colored green, yellow, and red, respectively.
