Fig. 5: Analysis of B cells from BMMCs and paired PBMCs and production of SARS-CoV-2-specific antibody in COVID-19 patients. | Cell Discovery

Fig. 5: Analysis of B cells from BMMCs and paired PBMCs and production of SARS-CoV-2-specific antibody in COVID-19 patients.

From: Dysregulated hematopoiesis in bone marrow marks severe COVID-19

Fig. 5

a UMAP plot of B cells from BMMCs and PBMCs. b, c Proportion of B cells among total cells and three types of B cells among total B cells, with results from PBMC samples (b) and BMMC samples (c). d Somatic hypermutation rate of IGHV, IGKV, and IGLV from three groups and two origins. e Total SARS-CoV-2-specific antibody titers and SARS-CoV-2-specific IgG titers of six patients at different time points after symptom onset. The BM puncture was done between the 18th and 31st day after symptom onset.

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