Fig. 6: Variants in TUBB8 C-terminal tail were identified in patients with recurrent miscarriages.
From: Ectopic expression of human TUBB8 leads to increased aneuploidy in mouse oocytes
a Rates of carrying TUBB8 C-terminal variants in patients with recurrent miscarriages and in control subjects. Fisher’s exact test. b Schematic diagram of the TUBB8 C-terminal tail. Arrowheads indicate the rare variants at amino acids of 435 and 438 in patients with recurrent miscarriages. c All variants were confirmed by Sanger sequencing. Squares indicate males, and circles indicate females. Black circles indicate affected individuals, and triangles indicate aborted fetuses. Question marks refer to unavailable DNA samples.
