Fig. 1: Structural representations of the MCH‒MCHR1‒Gi and MCH‒MCHR2‒Gq complexes. | Cell Discovery

Fig. 1: Structural representations of the MCH‒MCHR1‒Gi and MCH‒MCHR2‒Gq complexes.

From: Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors

Fig. 1

a Depiction of the MCH sequence and a schematic representation illustrating the G-protein coupling of MCHR1 and MCHR2. b, c Cryo-EM density map (b) and the corresponding molecular model (c) of the MCH‒MCHR1‒Gi complex. d, e Cryo-EM density map (d) and the corresponding molecular model (e) of the MCH‒MCHR2‒Gq complex.

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