Fig. 2: Inversions detected by NanoStrand-seq. | Cell Discovery

Fig. 2: Inversions detected by NanoStrand-seq.

From: Simultaneous de novo calling and phasing of genetic variants at chromosome-scale using NanoStrand-seq

Fig. 2

a Histogram displaying the number of putative homozygous inversions and putative heterozygous inversions detected by NanoStrand-seq at a given cell number. b Box plot showing the length of putative homozygous inversions and putative heterozygous inversions detected by NanoStrand-seq at the given cell number. Each spot denotes a single inversion event. c Venn diagram showing the consistency between the confident inversions detected by NanoStrand-seq and inversion call set of GM12878 of Porubsky et al. 2022 in Cell34 (presumed to be the ground truth for GM12878 inversions). d Examples of the putative homozygous inversion located on Chr8 (top) and putative heterozygous inversion located on Chr7 (bottom) detected by NanoStrand-seq. e Ideogram plot displaying putative inversions on each chromosome34 detected by NanoStrand-seq (left panel). The total length of putative homozygous inversions and putative heterozygous inversions were shown in the right panel.

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