Fig. 3: GC content and the histone acetylation level influence nucleosome establishment and repositioning in mouse pronuclei, respectively. | Cell Research

Fig. 3: GC content and the histone acetylation level influence nucleosome establishment and repositioning in mouse pronuclei, respectively.

From: Dynamic nucleosome organization after fertilization reveals regulatory factors for mouse zygotic genome activation

Fig. 3

a Boxplots showing the GC content of newly established nucleosome regions at each PN stage. Dashed lines represent the average GC content in genome. b Bar plot showing the association of different histone modifications and GC content with promoter NDR scores. c–e Nucleosome profiles around TSSs of all Refseq genes at 6 hpf (c) and 12 hpf (d), or genes of the indicated promoter NDR clusters at 6 hpf (e; defined in Supplementary information, Fig. S6f) in parental PN from groups under different treatments. JQ1-B1, JQ1 batch 1; JQ1-B2, JQ1 batch 2; DMSO, 0.05% dimethyl sulfoxide-treated; control, water-injected.

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