Fig. 1

Pathogen-sensing machinery expression in human DC populations in the human myeloid scRNA atlas. A Visualization of PhenoGraph clusters on an MNP-VERSE UMAP plot following the coordinates presented by Mulder et al., 2021. Briefly, MNP-VERSE was downloaded from https://github.com/gustaveroussy/FG-Lab, and the data were explored with Seurat v4.2 (Hao and Hao et al. 2021, https://doi.org/10.1016/j.cell.2021.04.048). For simplicity, monocyte and macrophage clusters were unified. Bottom left, cells derived from cells enriched in cell cycle-related genes were unlabelled. B DotPlot presenting the normalized expression of TLRs from the MNP-VERSE. C DotPlot presenting the normalized expression of dsDNA machinery sensing from the MNP-VERSE