Table 2 Comparisons of clinicopathological features between lynch and sporadic CRC.
Factors |  | Lynch (n = 23) | Sporadic (n = 86) | P value |
|---|---|---|---|---|
Age | Mean | 46.8 | 55.8 | 0.001 |
Sex | Â | Â | Â | 0.755 |
| Â | Female | 11 (47.8) | 38 (44.2) | Â |
| Â | Male | 12 (52.2) | 48 (55.8) | Â |
Sideness | Â | Â | Â | 0.993 |
| Â | Left | 8 (34.8) | 30 (34.9) | Â |
| Â | Right | 15 (65.2) | 56 (65.1) | Â |
Mucinous | Â | Â | Â | 0.019 |
| Â | Yes | 4 (17.4) | 38 (44.2) | Â |
| Â | No | 19 (82.6) | 48 (55.8) | Â |
BRAF mutation | Â | Â | Â | 0.193 |
| Â | Mutant-type | 0 (0.0) | 6 (7.0) | Â |
| Â | Wild-type | 23 (100.0) | 80 (93.0) | Â |
MLH1 methylation | Â | Â | Â | <0.001 |
| Â | Methylated | 1 (4.3) | 39 (45.3) | Â |
| Â | Nonmethylated | 22 (95.7) | 47 (54.7) | Â |
Revised Bethesda Criteria | Â | Â | Â | Â |
| Â | Met | 20 (87.0) | 36 (41.9) | <0.001 |
| Â | Unmet | 3 (13.0) | 50 (58.1) | Â |
History of polyps | Â | Â | Â | 0.484 |
| Â | Yes | 9 (39.1) | 27 (31.4) | Â |
| Â | No | 14 (60.9) | 59 (68.6) | Â |
Cancer history of FDR | Â | Â | Â | <0.001 |
| Â | Yes | 15 (65.2) | 20 (23.3) | Â |
| Â | No | 8 (34.8) | 66 (76.7) | Â |
