Fig. 3: Bowing of long bones in the affected individuals.
From: Biallelic variants in CCN2 underlie an autosomal recessive kyphomelic dysplasia
Radiographs of limbs of probands: proband 1 at 15 years (A), proband 2 at 11 years (B) and proband 3 at 3 years of age (C–F) show bowing of long bones. Bowing of femur (A and B), bowing of the tibia and fibula (A, C, D) can be observed. Irregular epiphyses and metaphyses along with flaring of metaphyses at the knee joint can be noted (D). Variable platyspondyly can be observed in all (G–I).
