Fig. 3 | Eye

Fig. 3

From: A two-year study of diffused retinal pigment epitheliopathy treated with half-dose photodynamic therapy guided by simultaneous angiography and optical coherence tomography

Fig. 3

A 38-year-old male with diffused retinal pigment epitheliopathy for 14 months and deteriorated over recent 1 month. a, b Early-phase angiography showed diffused hyperfluorescence across the posterior region in fluoroscein angiography (FA) and choroidal vascular dilation in indocyanine green angiography (ICGA). c, d Mid-phase images showed at least 11 active fluorescein leaks and intense choroidal hyperpermeability staining. e–h At 3 months, the FA and ICGA images showed no active fluorescein leaks despite the persistent choroidal vascular dilation. Optical coherence tomograpgy images: i at baseline, external limiting membrane (ELM): fragmented; j at 3 months, ELM: fragmented, ellipsoid zone (EZ): absent, interdigitation zone (IZ): absent; k at 6 months, ELM: fragmented, EZ: fragmented, IZ: absent; l at 12 months, ELM: continuous, EZ: fragmented, IZ: absent; m at 24 months, ELM: continuous, EZ: fragmented, IZ: fragmented. The subretinal fluid absorbed at 3 months without recurrence, and best-corrected visual acuity (logarithms of the minimum angle of resolution) was 0.15, 0.40, 0.22, −0.08 and −0.20 at each visit

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