Fig. 4: Human CFTR mRNA is detected in LV-CFTR treated ALI cultures. | Gene Therapy

Fig. 4: Human CFTR mRNA is detected in LV-CFTR treated ALI cultures.

From: Lentiviral vector gene therapy and CFTR modulators show comparable effectiveness in cystic fibrosis rat airway models

Fig. 4

Absolute quantification of A human and B rat CFTR mRNA in untreated and LV-CFTR treated rat ALIs. Total copy number is expressed relative to the total copy number of the housekeeping gene CycA. Data are represented as mean ± SEM, one-way ANOVA, Tukey’s multiple comparison test, ns: not significant, ***p < 0.001, ****p < 0.0001, n = 2–5 per group. F508; Phe508del.

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