Table 1 Allele frequency in the mixture

From: Inferring fetal fractions from read heterozygosity empowers the noninvasive prenatal screening

MM-FF

Prob

fA

AA-AA

p3

1

AB-AB

p(1 − p)

1/2

BB-BB

\((1 - p)^3\)

0

AA-AB

\(p^2(1 - p)\)

1 − h/2

BB-AB

\(p(1 - p)^2\)

h/2

AB-AA

\(p^2(1 - p)\)

1/2 + h/2

AB-BB

\(p(1 - p)^2\)

1/2 − h/2

  1. Note joint genotypes AA-BB and BB-AA are Mendelian incompatible and excluded from the table.
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