Fig. 1: CSF NEFL level in samples from CLN3 versus non-CLN3 (PLC, CTD, SLOS) individuals, measured by enzyme-linked immunosorbent assay (ELISA). | Genetics in Medicine

Fig. 1: CSF NEFL level in samples from CLN3 versus non-CLN3 (PLC, CTD, SLOS) individuals, measured by enzyme-linked immunosorbent assay (ELISA).

From: Neurofilament light chain levels correlate with clinical measures in CLN3 disease

Fig. 1

Black diamond—mean; blue diamond—outlier; box—median and interquartile range (IQR, Q1 [25th percentile]–Q3 [75th percentile]); whiskers—minimum = Q1 – 1.5*IQR and maximum = Q3 + 1.5*IQR. P values are derived from analysis of variance (ANOVA) and post hoc Bonferroni adjustment for pairwise multiple comparisons. CSF cerebrospinal fluid, CTD creatine transport deficiency, ELISA enzyme-linked immunosorbent assay, NEFL neurofilament light chain, PLC pediatric laboratory controls, SLOS Smith–Lemli–Opitz syndrome.

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