Fig. 2: Serum NEFL level in samples from CLN3 versus non-CLN3 (PHS, CTD, SLOS) individuals, measured by SimoaTM. | Genetics in Medicine

Fig. 2: Serum NEFL level in samples from CLN3 versus non-CLN3 (PHS, CTD, SLOS) individuals, measured by SimoaTM.

From: Neurofilament light chain levels correlate with clinical measures in CLN3 disease

Fig. 2

Black circle—mean; blue circle—outlier; box—median and interquartile range (IQR, Q1 [25th percentile] – Q3 [75th percentile]); whiskers—minimum = Q1 – 1.5*IQR and maximum = Q3 + 1.5*IQR. P values are derived from analysis of variance (ANOVA) and post hoc Bonferroni adjustment for multiple pairwise comparisons. CSF cerebrospinal fluid, CTD creatine transport deficiency, NEFL neurofilament light chain, PHS pediatric healthy (unaffected) siblings, SLOS Smith–Lemli–Opitz syndrome.

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