Table 3 Numbers and percentages of women per 10-year risk category.

From: Validation of the BOADICEA model and a 313-variant polygenic risk score for breast cancer risk prediction in a Dutch prospective cohort

  

10-year risk category based on BOADICEA

 

Total

Including age and PRS

Including age, risk factors, and PRS

  

<2.5%

>2.5%

<2.5%

>2.5%

Unaffected women

All

4214

1481 (35%)

2733 (65%)

2359 (56%)

1855 (44%)

Incident BC cases

All

163

33 (20%)

130 (80%)

62 (38%)

101 (62%)

Invasive BC

All

142

30 (21%)

112 (79%)

52 (37%)

90 (63%)

Grade 1

19

2 (11%)

17 (89%)

3 (16%)

16 (84%)

Grade 2

38

7 (18%)

31 (82%)

12 (32%)

26 (68%)

Grade 3

43

13 (30%)

30 (70%)

21 (49%)

22 (51%)

Unknown

42

8 (19%)

34 (81%)

16 (38%)

26 (62%)

In situ BC

All

21

3 (14%)

18 (86%)

10 (48%)

11 (52%)

Grade 1

3

2 (67%)

1 (33%)

2 (67%)

1 (33%)

Grade 2

3

1 (33%)

2 (67%)

2 (67%)

1 (33%)

Grade 3

13

0 (0%)

13 (100%)

5 (38%)

8 (62%)

Unknown

2

0 (0%)

2 (100%)

1 (50%)

1 (50%)

  1. BC breast cancer, BOADICEA Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm, PRS polygenic risk score.