Fig. 5: Univariate assessed and heritable breast cancer risk distributions by type of family history information provided to BOADICEA and by high-risk threshold (Hi-RT, the multiple of the age-specific absolute risk of breast cancer incidence). | Genetics in Medicine

Fig. 5: Univariate assessed and heritable breast cancer risk distributions by type of family history information provided to BOADICEA and by high-risk threshold (Hi-RT, the multiple of the age-specific absolute risk of breast cancer incidence).

From: Potential of polygenic risk scores for improving population estimates of women’s breast cancer genetic risks

Fig. 5

In all cases, the risk assessment is for women aged 40 and with both pathogenic variant (PV) and polygenic risk score (PRS) proband information provided to BOADICEA.

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