Fig. 1 | Hypertension Research

Fig. 1

From: Home blood pressure-lowering effect of esaxerenone vs trichlormethiazide for uncontrolled hypertension: a prespecified subanalysis of the EXCITE-HT randomized controlled study by age subgroup

Fig. 1

Changes from baseline to EOT in (A, B, C, D) morning home, (E, F) bedtime home, and (G, H) office BP (full analysis set). (A, C, E, G) Subgroup aged <65 years; (B, D, F, H) subgroup aged ≥65 years. For (C, D), the red dotted line (3.9 mmHg) and blue dotted line (2.1 mmHg) indicate the non-inferiority criteria. Data are LS mean (95% CI) for (A–D). Data are arithmetic mean (95% CI) for (E–H). ***P < 0.001 versus baseline, paired t-test. BP blood pressure, CI confidence interval, DBP diastolic blood pressure, EOT end of treatment, LS least squares, SBP systolic blood pressure

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