Fig. 2 | Nature Communications

Fig. 2

From: Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

Fig. 2

Bayesian networks of HAEC reveal novel key drivers in response to oxidized phospholipids. a, b Network view of HAEC Bayesian network of control state (a) and oxPAPC-treated state (b). Key drivers with more than 100 downstream nodes are indicated and ten top-ranked subnetworks according to strength of enrichment and subnetwork size are colored. Edges are colored according to source node. c, d List of ten subnetworks colored within control (c) and oxPAPC (d) Bayesian network with most top key driver, number of nodes, most significant overrepresented functional category and p value are listed

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