Table 2 Association between genes within the MTHFD2 network and CAD risk loci

From: Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

Gene

SNP

p value

SORT1

rs7528419, rs12740374, rs4970834, rs611917

7.05E-08, 1.25E-07, 1.04E-06, 1.45E-06

SLC7A1

rs9551751

7.93E-08

SHMT2

rs11172113

1.72E-06

DDIT3

rs11172113

1.72E-06

MARS

rs11172113

1.72E-06

CEBPB

rs6095611, rs1034056, rs6067199, rs6091031

9.14E-06, 1.38E-05, 1.59E-05, 1.75E-05

FOXO1

rs9594389, rs7323896

1.68E-05, 1.78E-05

GJA4

rs1336624

2.42E-05

CDC42EP2

rs12419237

4.82E-05

PIK3C2B

rs16854023

5.57E-05