Fig. 7
From: A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression

Upregulation of CD47 on Friend virus (FV)-infected splenocytes. Mice were infected with FV or left naive and the splenocytes were analyzed by flow cytometry to compare the mean fluorescence intensity of CD47 on naive or FV-infected (Virus+) and uninfected (Virusā) total splenocytes at 7 days post-infectionĀ (dpi) with significance as indicated by one-way analysis of variance. Virus was detected by cell surface expression of glycosylated gag antigen with mAb 34 as described in Methods. Data from one of four independent experiments are shown.Ā ns, ****pāā¤ā0.0001 (unpaired, two-way t tests)