Fig. 1
From: Neuroepigenetic signatures of age and sex in the living human brain
[11C]Martinostat uptake increases with age in the white matter. Voxel-wise correlations of SUVR with age, controlled for sex, total grey matter volume/intracranial volume, white matter volume/intracranial volume, and cerebrospinal fluid volume/intracranial volume (n = 41). Statistical maps were overlaid onto the MNI 1 mm template in radiological orientation (family wise error rate (FWE) corrected for multiple comparisons, PFWE < 0.05; non-parametric permutation testing n = 10,000 permutations). Red–yellow represents regions significantly increased with age
