Fig. 4

Heat map clustering of co-localization analysis results. GTex-based eQTL results from Ensemble REST API is used between nearest gene to the lead SNPs and each SNP in 200 KB region surrounding lead SNPs. Rows show lead SNP-nearest gene combinations for which eQTL is obtained. Columns show tissues from which eQTL is obtained. If achieved, posterior probabilities >0.75 is colored for H0 (yellow; on association with either trait), H1 (gray; association with urinary trait, not with gene expression), H2 (gray; association with gene expression, not with urinary trait), H3 (pink; association with urinary trait and gene expression, two independent SNPs), and H4 (red; association with urinary trait and gene expression, one shared SNP). Black cells show missing eQTL information. a Heat map clustering based on co-localization for urinary sodium loci. b Heat map clustering based on co-localization for urinary potassium