Fig. 2
From: Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease
PKD1-KO monkeys show enlarged kidneys with numerous cysts. a Enlarged kidneys in monkeys with severe-type kidneys. b Ultrasonography of the kidneys. “L” indicates left kidneys and “R” indicates right kidneys. c The gross appearances and cross-sections of severe-type kidneys and WT kidneys on the same scale. d The immature lungs of monkeys with severe-type kidneys and a WT monkey on the same scale. “Day” indicates the day of abortion. e H&E-stained image of the kidneys. “G” indicates glomeruli and “Cy” indicates cysts. Scale bar, 100 µm. f The expressions of AQP1, AQP2, and PC1 in a severe-type kidney. Asterisks indicate cysts. Scale bar, 100 µm. g Liver cysts. “Cy” indicates cysts. Scale bar, 100 µm. h A pancreatic cyst. “Cy” indicates a cyst and “D” indicates a duct. Scale bar, 100 µm.
