Fig. 1: Identification and functional prediction of human liver lnc-eGenes. | Nature Communications

Fig. 1: Identification and functional prediction of human liver lnc-eGenes.

From: In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits

Fig. 1

a Flowchart depicting a pipeline for identifying potentially functional human lncRNAs by integration of GWAS and eQTL data and by further bioinformatic and experimental analyses. b Heatmap of tissue expression Z score for the cardiometabolic trait-associated lnc-eGenes. LINC01018 and liver tissue were pointed out by red arrows. c Co-expression module analysis of cardiometabolic trait-associated lnc-eGenes. The modules with at least one significant KEGG pathway and including 2 or more trait associated lnc-eGenes are shown. d KEGG pathway analysis of protein-coding genes in each module; only the top two most significant pathway for each module are displayed.

Back to article page