Fig. 2: HSD increased tissue osmotic stress via promoting NaCl accumulation. | Nature Communications

Fig. 2: HSD increased tissue osmotic stress via promoting NaCl accumulation.

From: High-salt diet inhibits tumour growth in mice via regulating myeloid-derived suppressor cell differentiation

Fig. 2

a, b Na+ and Cl− content in different organs compared with plasma concentrations in the same mice when 4T1 tumour-bearing mice were fed the NSD and HSD for 16 days. c Na+, K+ and Cl− content in tumour tissues was determined by X-ray fluorescence spectrometry. d The osmolality of tissues from 4T1 tumour-bearing mice was examined by vapour-pressure osmometry. For all panels, the two-tailed Wilcoxon rank-sum tests; n = 10 mice per group; ns not significant; *p < 0.05, **p < 0.01 and ***p < 0.001. These experiments were replicated with a comparable number of mice three times. Data are representative of three independent experiments, and are presented as the mean ± SEM. Source data are provided as a Source Data file.

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