Fig. 5: The impact of tumor fraction and tumor content on the detectability of dark channel biomarker genes in cell-free RNA.

Patient IDs plotted as a function of tumor fraction (triangles) and tumor content (squares) for a FABP7 and b SCGB2A2. Patient IDs are ranked in descending order based on patient-specific tumor fractions and are ordered identically in both panels. Blue and red symbols represent samples for which either FABP7 or SCGB2A2 was detected in plasma, respectively.