Fig. 3: Reaction scale-up and product transformations.

Reaction conditions: ^amesitylene (260 mmol), P(OEt)₃ (5 equiv), HBF₄ (2 equiv), H₂O (2 equiv), MeCN, rt, 231 h. ^bTMSBr, MeCN. ^cSOCl₂, DMF, reflux. ^dPhMgBr, THF. ^eHOCH₂CH₂CH₂NH₂, Et₃N, THF. ^f(HOCH₂)₂CMe₂, Et₃N, THF. ^g(MeNHCH₂)₂, Et₃N, THF. TMSBr trimethylsilyl bromide. THF tetrahydrofuran.