Fig. 6: The localization of different mutant WFS1 proteins in HEK-293T cells.
From: WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells
Pairwise expression of KDEL-Dsred and mutant WFS1-GFP (WT, ΔNT, ΔCT, E158K, E169K, G695V, P724L, E809K, and E830K) revealed that the ΔNT, E158K, or E169K mutation severely disrupted ER localization of WFS1. n = 3 independent experiments. Scale bar, 10 μm.
