Fig. 2: Assessment of Fab ch128.1/IgG1 and MACV GP1-Fc for binding to sTfR1 by bio-layer interferometry. | Nature Communications

Fig. 2: Assessment of Fab ch128.1/IgG1 and MACV GP1-Fc for binding to sTfR1 by bio-layer interferometry.

From: Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections

Fig. 2

MACV GP1-Fc immobilized onto anti-human Fc biosensor tips and incubated with (a) sTfR1 or (b) buffer alone, (c) sTfR1 in complex with Fab ch128.1/IgG1 or (d) Fab ch128.1/IgG1 alone, or (e) sTfR1 in complex with Tf or (f) Tf alone. The arrows indicate the time points at which the indicated proteins were added and the dissociation step. The experiment was performed twice with representative data from one of the experiments shown. Seconds (s). Source data are included in the Source Data file.

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